P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 S 0 19 19 0.981 0.933 View mutations
177 L 0 19 19 0.999 0.987 View mutations
178 F 0 19 19 0.999 0.953 View mutations
179 L 0 19 19 0.996 0.957 View mutations
180 P 0 19 19 1.000 0.969 View mutations
181 R 5 14 19 0.695 0.646 View mutations
182 V 4 15 19 0.809 0.639 View mutations
183 L 6 13 19 0.650 0.599 View mutations
184 D 4 15 19 0.760 0.574 View mutations
185 H 19 0 19 0.012 0.470 View mutations
186 R 19 0 19 0.039 0.460 View mutations
187 D 8 11 19 0.599 0.525 View mutations
188 H 13 6 19 0.381 0.466 View mutations
189 E 4 15 19 0.805 0.467 View mutations
190 M 9 10 19 0.518 0.430 View mutations
191 V 4 15 19 0.766 0.455 View mutations
192 R 9 10 19 0.512 0.448 View mutations
193 Q 18 1 19 0.060 0.568 View mutations
194 L 9 10 19 0.515 0.447 View mutations
195 Q 19 0 19 0.040 0.723 View mutations
196 S 17 2 19 0.106 0.710 View mutations
197 G 19 0 19 0.015 0.810 View mutations
198 L 19 0 19 0.009 0.878 View mutations
199 P 19 0 19 0.023 0.931 View mutations
200 R 19 0 19 0.041 0.918 View mutations