P16401 (P16401)

Overview
Predicted structure (AF):
AF-P16401-F1-model_v4
Uniprot entry:
P16401
Gene:
P16401
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2597 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1696 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2597 benign and 1696 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 K 18 1 19 0.092 0.900 View mutations
27 K 19 0 19 0.011 0.957 View mutations
28 A 18 1 19 0.090 0.908 View mutations
29 A 18 1 19 0.184 0.891 View mutations
30 G 18 1 19 0.075 0.878 View mutations
31 A 19 0 19 0.009 0.906 View mutations
32 G 19 0 19 0.008 0.865 View mutations
33 A 17 2 19 0.192 0.793 View mutations
34 A 19 0 19 0.004 0.846 View mutations
35 K 16 3 19 0.210 0.726 View mutations
36 R 16 3 19 0.231 0.652 View mutations
37 K 16 3 19 0.142 0.555 View mutations
38 A 5 14 19 0.717 0.402 View mutations
39 T 3 16 19 0.782 0.418 View mutations
40 G 0 19 19 0.976 0.561 View mutations
41 P 0 19 19 0.988 0.612 View mutations
42 P 17 2 19 0.141 0.401 View mutations
43 V 15 4 19 0.208 0.494 View mutations
44 S 3 16 19 0.814 0.473 View mutations
45 E 0 19 19 0.977 0.541 View mutations
46 L 6 13 19 0.722 0.525 View mutations
47 I 2 17 19 0.880 0.518 View mutations
48 T 1 18 19 0.897 0.513 View mutations
49 K 0 19 19 0.973 0.500 View mutations
50 A 2 17 19 0.905 0.567 View mutations