P16401 (P16401)

Overview
Predicted structure (AF):
AF-P16401-F1-model_v4
Uniprot entry:
P16401
Gene:
P16401
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2597 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1696 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2597 benign and 1696 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 11 7 18 0.491 0.412 View mutations
2 S 8 11 19 0.548 0.433 View mutations
3 E 0 19 19 1.000 0.488 View mutations
4 T 8 11 19 0.536 0.433 View mutations
5 A 12 7 19 0.371 0.470 View mutations
6 P 14 5 19 0.254 0.512 View mutations
7 A 19 0 19 0.002 0.750 View mutations
8 E 19 0 19 0.004 0.786 View mutations
9 T 19 0 19 0.032 0.800 View mutations
10 A 19 0 19 0.042 0.813 View mutations
11 T 19 0 19 0.003 0.845 View mutations
12 P 13 6 19 0.315 0.613 View mutations
13 A 19 0 19 0.009 0.817 View mutations
14 P 18 1 19 0.078 0.783 View mutations
15 V 19 0 19 0.000 0.861 View mutations
16 E 19 0 19 0.000 0.806 View mutations
17 K 18 1 19 0.071 0.847 View mutations
18 S 17 2 19 0.124 0.833 View mutations
19 P 16 3 19 0.268 0.738 View mutations
20 A 19 0 19 0.002 0.931 View mutations
21 K 11 8 19 0.475 0.575 View mutations
22 K 19 0 19 0.068 1.000 View mutations
23 K 17 2 19 0.115 0.876 View mutations
24 A 18 1 19 0.170 0.897 View mutations
25 T 19 0 19 0.080 0.951 View mutations