P16401 (P16401)

Overview
Predicted structure (AF):
AF-P16401-F1-model_v4
Uniprot entry:
P16401
Gene:
P16401
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2597 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1696 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4293 mutations across 226 unique positions. There are 2597 benign and 1696 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 V 0 19 19 1.000 0.553 View mutations
52 A 2 17 19 0.855 0.542 View mutations
53 A 1 18 19 0.934 0.651 View mutations
54 S 0 19 19 1.000 0.649 View mutations
55 K 9 10 19 0.508 0.508 View mutations
56 E 1 18 19 0.937 0.675 View mutations
57 R 0 19 19 1.000 0.600 View mutations
58 N 7 12 19 0.634 0.528 View mutations
59 G 0 19 19 1.000 0.723 View mutations
60 L 2 17 19 0.891 0.632 View mutations
61 S 0 19 19 1.000 0.739 View mutations
62 L 0 19 19 1.000 0.780 View mutations
63 A 1 18 19 0.926 0.708 View mutations
64 A 0 19 19 0.999 0.721 View mutations
65 L 0 19 19 1.000 0.717 View mutations
66 K 0 19 19 1.000 0.744 View mutations
67 K 0 19 19 1.000 0.753 View mutations
68 A 3 16 19 0.871 0.575 View mutations
69 L 1 18 19 0.944 0.705 View mutations
70 A 2 17 19 0.868 0.664 View mutations
71 A 0 19 19 1.000 0.767 View mutations
72 G 2 17 19 0.862 0.630 View mutations
73 G 0 19 19 1.000 0.928 View mutations
74 Y 0 19 19 1.000 0.880 View mutations
75 D 0 19 19 1.000 0.860 View mutations