P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 Y 13 6 19 0.308 0.523 View mutations
227 Y 19 0 19 0.001 0.624 View mutations
228 R 19 0 19 0.009 0.624 View mutations
229 L 2 17 19 0.906 0.530 View mutations
230 T 15 4 19 0.243 0.482 View mutations
231 R 18 1 19 0.053 0.436 View mutations
232 F 17 2 19 0.136 0.387 View mutations
233 L 0 19 19 1.000 0.763 View mutations
234 S 0 19 19 0.973 0.586 View mutations
235 R 18 1 19 0.057 0.492 View mutations
236 V 18 1 19 0.084 0.394 View mutations
237 I 4 15 19 0.754 0.600 View mutations
238 K 11 8 19 0.472 0.493 View mutations
239 C 3 16 19 0.809 0.613 View mutations
240 D 7 12 19 0.621 0.556 View mutations
241 P 19 0 19 0.006 0.414 View mutations
242 D 18 1 19 0.196 0.372 View mutations
243 C 16 3 19 0.226 0.389 View mutations
244 L 18 1 19 0.060 0.140 View mutations
245 R 13 6 19 0.358 0.478 View mutations
246 A 12 7 19 0.376 0.470 View mutations
247 C 18 1 19 0.085 0.232 View mutations
248 Q 5 14 19 0.704 0.635 View mutations
249 E 0 19 19 0.970 0.758 View mutations
250 Q 2 17 19 0.879 0.605 View mutations