P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.011 0.436 View mutations
2 E 17 2 19 0.122 0.595 View mutations
3 H 7 12 19 0.652 0.416 View mutations
4 Q 13 6 19 0.361 0.450 View mutations
5 L 19 0 19 0.017 0.467 View mutations
6 L 19 0 19 0.001 0.373 View mutations
7 C 19 0 19 0.001 0.372 View mutations
8 C 19 0 19 0.003 0.554 View mutations
9 E 19 0 19 0.053 0.410 View mutations
10 V 19 0 19 0.003 0.667 View mutations
11 E 19 0 19 0.000 0.651 View mutations
12 T 17 2 19 0.098 0.648 View mutations
13 I 19 0 19 0.002 0.601 View mutations
14 R 19 0 19 0.006 0.619 View mutations
15 R 19 0 19 0.000 0.537 View mutations
16 A 19 0 19 0.000 0.485 View mutations
17 Y 18 1 19 0.044 0.534 View mutations
18 P 19 0 19 0.000 0.517 View mutations
19 D 17 2 19 0.155 0.413 View mutations
20 A 19 0 19 0.001 0.420 View mutations
21 N 12 7 19 0.442 0.426 View mutations
22 L 19 0 19 0.006 0.357 View mutations
23 L 16 3 19 0.176 0.417 View mutations
24 N 17 2 19 0.221 0.463 View mutations
25 D 6 13 19 0.654 0.557 View mutations