P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 I 2 17 19 0.840 0.843 View mutations
252 E 18 1 19 0.136 0.291 View mutations
253 A 17 2 19 0.178 0.494 View mutations
254 L 17 2 19 0.110 0.305 View mutations
255 L 6 13 19 0.667 0.630 View mutations
256 E 12 7 19 0.413 0.486 View mutations
257 S 17 2 19 0.201 0.368 View mutations
258 S 17 2 19 0.087 0.389 View mutations
259 L 15 4 19 0.201 0.352 View mutations
260 R 16 3 19 0.208 0.467 View mutations
261 Q 19 0 19 0.034 0.625 View mutations
262 A 13 6 19 0.299 0.504 View mutations
263 Q 19 0 19 0.074 0.784 View mutations
264 Q 19 0 19 0.039 0.907 View mutations
265 N 19 0 19 0.005 0.909 View mutations
266 M 19 0 19 0.001 0.944 View mutations
267 D 17 2 19 0.092 0.847 View mutations
268 P 19 0 19 0.001 0.992 View mutations
269 K 18 1 19 0.069 0.947 View mutations
270 A 19 0 19 0.005 0.979 View mutations
271 A 19 0 19 0.010 0.936 View mutations
272 E 19 0 19 0.005 0.963 View mutations
273 E 19 0 19 0.001 0.914 View mutations
274 E 18 1 19 0.055 0.843 View mutations
275 E 19 0 19 0.013 0.846 View mutations