P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 I 4 15 19 0.740 0.621 View mutations
127 Y 0 19 19 0.975 0.708 View mutations
128 T 0 19 19 1.000 0.780 View mutations
129 D 3 16 19 0.751 0.643 View mutations
130 N 1 18 19 0.929 0.605 View mutations
131 S 0 19 19 0.991 0.662 View mutations
132 I 2 17 19 0.902 0.580 View mutations
133 R 19 0 19 0.045 0.480 View mutations
134 P 17 2 19 0.131 0.439 View mutations
135 E 19 0 19 0.001 0.608 View mutations
136 E 19 0 19 0.073 0.511 View mutations
137 L 1 18 19 0.957 0.535 View mutations
138 L 16 3 19 0.209 0.377 View mutations
139 Q 19 0 19 0.026 0.595 View mutations
140 M 14 5 19 0.301 0.498 View mutations
141 E 3 16 19 0.775 0.632 View mutations
142 L 19 0 19 0.001 0.399 View mutations
143 L 19 0 19 0.000 0.446 View mutations
144 L 10 9 19 0.438 0.490 View mutations
145 V 19 0 19 0.088 0.187 View mutations
146 N 19 0 19 0.005 0.370 View mutations
147 K 9 10 19 0.491 0.506 View mutations
148 L 19 0 19 0.000 0.098 View mutations
149 K 19 0 19 0.045 0.289 View mutations
150 W 19 0 19 0.000 0.225 View mutations