P24385 (P24385)

Overview
Predicted structure (AF):
AF-P24385-F1-model_v4
Uniprot entry:
P24385
Gene:
P24385
Protein length:
295 residues
Mutations found:
5604
Benign based on D2Deep prediction:
3437 out of 5604 mutations
Pathogenic based on D2Deep prediction:
2167 out of 5604 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5604 mutations across 295 unique positions. There are 3437 benign and 2167 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 E 2 17 19 0.862 0.639 View mutations
77 V 3 16 19 0.808 0.668 View mutations
78 F 0 19 19 1.000 0.673 View mutations
79 P 0 19 19 0.985 0.674 View mutations
80 L 0 19 19 0.999 0.744 View mutations
81 A 0 19 19 0.989 0.722 View mutations
82 M 1 18 19 0.938 0.655 View mutations
83 N 0 19 19 1.000 0.743 View mutations
84 Y 8 11 19 0.618 0.517 View mutations
85 L 3 16 19 0.816 0.629 View mutations
86 D 0 19 19 0.999 0.802 View mutations
87 R 5 14 19 0.752 0.594 View mutations
88 F 10 9 19 0.449 0.424 View mutations
89 L 14 5 19 0.239 0.402 View mutations
90 S 19 0 19 0.029 0.414 View mutations
91 L 17 2 19 0.140 0.473 View mutations
92 E 18 1 19 0.028 0.454 View mutations
93 P 16 3 19 0.196 0.433 View mutations
94 V 19 0 19 0.001 0.436 View mutations
95 K 3 16 19 0.785 0.336 View mutations
96 K 0 19 19 0.993 0.543 View mutations
97 S 19 0 19 0.025 0.465 View mutations
98 R 17 2 19 0.124 0.532 View mutations
99 L 5 14 19 0.715 0.550 View mutations
100 Q 4 15 19 0.747 0.623 View mutations