P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 15 3 18 0.190 0.425 View mutations
2 E 15 4 19 0.256 0.428 View mutations
3 L 1 18 19 0.942 0.415 View mutations
4 L 10 9 19 0.520 0.436 View mutations
5 C 9 10 19 0.487 0.436 View mutations
6 C 19 0 19 0.037 0.607 View mutations
7 E 19 0 19 0.047 0.539 View mutations
8 G 19 0 19 0.028 0.798 View mutations
9 T 19 0 19 0.057 0.807 View mutations
10 R 19 0 19 0.014 0.780 View mutations
11 H 19 0 19 0.002 0.839 View mutations
12 A 18 1 19 0.117 0.708 View mutations
13 P 18 1 19 0.087 0.765 View mutations
14 R 18 1 19 0.075 0.660 View mutations
15 A 19 0 19 0.001 0.581 View mutations
16 G 19 0 19 0.005 0.652 View mutations
17 P 19 0 19 0.006 0.646 View mutations
18 D 2 17 19 0.895 0.468 View mutations
19 P 17 2 19 0.160 0.431 View mutations
20 R 19 0 19 0.004 0.525 View mutations
21 L 2 17 19 0.894 0.511 View mutations
22 L 19 0 19 0.007 0.395 View mutations
23 G 12 7 19 0.407 0.459 View mutations
24 D 2 17 19 0.836 0.465 View mutations
25 Q 13 6 19 0.309 0.484 View mutations