P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 R 17 2 19 0.230 0.484 View mutations
27 V 19 0 19 0.008 0.362 View mutations
28 L 13 6 19 0.417 0.413 View mutations
29 Q 18 1 19 0.095 0.545 View mutations
30 S 11 8 19 0.444 0.439 View mutations
31 L 19 0 19 0.015 0.484 View mutations
32 L 17 2 19 0.103 0.407 View mutations
33 R 16 3 19 0.161 0.527 View mutations
34 L 19 0 19 0.022 0.542 View mutations
35 E 1 18 19 0.936 0.547 View mutations
36 E 19 0 19 0.020 0.494 View mutations
37 R 19 0 19 0.002 0.518 View mutations
38 Y 10 9 19 0.487 0.444 View mutations
39 V 5 14 19 0.683 0.424 View mutations
40 P 3 16 19 0.829 0.548 View mutations
41 R 9 10 19 0.550 0.438 View mutations
42 A 18 1 19 0.051 0.462 View mutations
43 S 19 0 19 0.000 0.384 View mutations
44 Y 1 18 19 0.944 0.593 View mutations
45 F 0 19 19 1.000 0.611 View mutations
46 Q 12 7 19 0.373 0.445 View mutations
47 C 14 5 19 0.358 0.419 View mutations
48 V 3 16 19 0.813 0.551 View mutations
49 Q 0 19 19 1.000 0.555 View mutations
50 R 3 16 19 0.855 0.420 View mutations