P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 1 18 19 0.947 0.506 View mutations
52 I 2 17 19 0.881 0.510 View mutations
53 K 9 10 19 0.485 0.445 View mutations
54 P 7 12 19 0.647 0.503 View mutations
55 H 19 0 19 0.001 0.541 View mutations
56 M 7 12 19 0.622 0.512 View mutations
57 R 0 19 19 1.000 0.565 View mutations
58 K 15 4 19 0.209 0.466 View mutations
59 M 11 8 19 0.382 0.468 View mutations
60 L 4 15 19 0.743 0.504 View mutations
61 A 1 18 19 0.943 0.447 View mutations
62 Y 5 14 19 0.761 0.400 View mutations
63 W 15 4 19 0.246 0.446 View mutations
64 M 18 1 19 0.112 0.383 View mutations
65 L 9 10 19 0.537 0.431 View mutations
66 E 9 10 19 0.505 0.503 View mutations
67 V 0 19 19 0.986 0.644 View mutations
68 C 0 19 19 1.000 0.692 View mutations
69 E 7 12 19 0.572 0.546 View mutations
70 E 8 11 19 0.565 0.525 View mutations
71 Q 1 18 19 0.952 0.584 View mutations
72 R 7 12 19 0.627 0.519 View mutations
73 C 0 19 19 1.000 0.629 View mutations
74 E 2 17 19 0.931 0.589 View mutations
75 E 1 18 19 0.940 0.662 View mutations