P31749 (AKT1) at position 12

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19 mutations found: 11 benign and 8 pathogenic.

D2Deep score mean: 0.388. Overall confidence mean: 0.520

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
L12A L 12 A 0.007 Benign based on D2Deep prediction 0.769 View mutation
L12C L 12 C 0.988 Pathogenic based on D2Deep prediction 0.178 View mutation
L12D L 12 D 0.011 Benign based on D2Deep prediction 0.769 View mutation
L12E L 12 E 0.019 Benign based on D2Deep prediction 0.769 View mutation
L12F L 12 F 0.006 Benign based on D2Deep prediction 0.769 View mutation
L12G L 12 G 0.082 Benign based on D2Deep prediction 0.769 View mutation
L12H L 12 H 1.000 Pathogenic based on D2Deep prediction 0.178 View mutation
L12I L 12 I 0.831 Pathogenic based on D2Deep prediction 0.178 View mutation
L12K L 12 K 0.634 Pathogenic based on D2Deep prediction 0.178 View mutation
L12M L 12 M 0.150 Benign based on D2Deep prediction 0.769 View mutation
L12N L 12 N 0.021 Benign based on D2Deep prediction 0.769 View mutation
L12P L 12 P 0.939 Pathogenic based on D2Deep prediction 0.178 View mutation
L12Q L 12 Q 0.125 Benign based on D2Deep prediction 0.769 View mutation
L12R L 12 R 0.652 Pathogenic based on D2Deep prediction 0.178 View mutation
L12S L 12 S 0.004 Benign based on D2Deep prediction 0.769 View mutation
L12T L 12 T 0.002 Benign based on D2Deep prediction 0.769 View mutation
L12V L 12 V 0.008 Benign based on D2Deep prediction 0.769 View mutation
L12W L 12 W 0.996 Pathogenic based on D2Deep prediction 0.178 View mutation
L12Y L 12 Y 0.900 Pathogenic based on D2Deep prediction 0.178 View mutation