P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.004 0.735 View mutations
2 S 19 0 19 0.018 0.895 View mutations
3 D 18 1 19 0.080 0.805 View mutations
4 V 19 0 19 0.031 0.987 View mutations
5 A 19 0 19 0.010 0.914 View mutations
6 I 19 0 19 0.001 0.853 View mutations
7 V 19 0 19 0.000 0.721 View mutations
8 K 19 0 19 0.021 0.821 View mutations
9 E 19 0 19 0.017 0.739 View mutations
10 G 18 1 19 0.176 0.661 View mutations
11 W 19 0 19 0.006 0.694 View mutations
12 L 11 8 19 0.388 0.520 View mutations
13 H 19 0 19 0.063 0.843 View mutations
14 K 1 18 19 0.954 0.277 View mutations
15 R 19 0 19 0.064 0.584 View mutations
16 G 19 0 19 0.068 0.506 View mutations
17 E 1 18 19 0.920 0.414 View mutations
18 Y 3 16 19 0.833 0.404 View mutations
19 I 3 16 19 0.816 0.475 View mutations
20 K 17 2 19 0.166 0.418 View mutations
21 T 1 18 19 0.930 0.446 View mutations
22 W 13 6 19 0.329 0.442 View mutations
23 R 1 18 19 0.926 0.431 View mutations
24 P 7 12 19 0.646 0.424 View mutations
25 R 0 19 19 0.999 0.517 View mutations