P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 I 6 13 19 0.700 0.607 View mutations
427 M 0 19 19 0.967 0.698 View mutations
428 S 0 19 19 0.979 0.581 View mutations
429 G 0 19 19 0.980 0.687 View mutations
430 R 10 9 19 0.490 0.497 View mutations
431 T 12 7 19 0.389 0.494 View mutations
432 D 6 13 19 0.679 0.567 View mutations
433 R 14 5 19 0.308 0.462 View mutations
434 L 10 9 19 0.512 0.494 View mutations
435 E 12 7 19 0.409 0.479 View mutations
436 H 12 7 19 0.324 0.494 View mutations
437 L 17 2 19 0.124 0.437 View mutations
438 E 2 17 19 0.885 0.535 View mutations
439 S 3 16 19 0.837 0.450 View mutations
440 Q 0 19 19 0.998 0.411 View mutations
441 E 0 19 19 0.997 0.504 View mutations
442 L 14 5 19 0.239 0.433 View mutations
443 D 6 13 19 0.654 0.451 View mutations
444 E 0 19 19 0.969 0.471 View mutations
445 Q 8 11 19 0.627 0.435 View mutations
446 I 15 4 19 0.178 0.452 View mutations
447 Y 8 11 19 0.596 0.436 View mutations
448 Q 11 8 19 0.468 0.430 View mutations
449 E 0 19 19 0.918 0.500 View mutations
450 D 1 18 19 0.939 0.551 View mutations