P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 Y 0 19 19 1.000 0.943 View mutations
402 Y 0 19 19 0.995 0.971 View mutations
403 K 0 19 19 1.000 0.884 View mutations
404 L 0 19 19 1.000 0.965 View mutations
405 N 4 15 19 0.837 0.736 View mutations
406 I 3 16 19 0.843 0.815 View mutations
407 I 1 18 19 0.944 0.930 View mutations
408 R 0 19 19 0.994 0.840 View mutations
409 K 2 17 19 0.905 0.857 View mutations
410 E 0 19 19 1.000 0.887 View mutations
411 P 0 19 19 1.000 0.961 View mutations
412 G 0 19 19 1.000 0.970 View mutations
413 Q 0 19 19 1.000 0.952 View mutations
414 R 0 19 19 1.000 0.911 View mutations
415 L 1 18 19 0.924 0.897 View mutations
416 L 0 19 19 1.000 0.904 View mutations
417 F 0 19 19 1.000 0.963 View mutations
418 R 0 19 19 0.987 0.849 View mutations
419 F 0 19 19 0.997 0.863 View mutations
420 M 1 18 19 0.964 0.754 View mutations
421 K 4 15 19 0.736 0.654 View mutations
422 T 13 6 19 0.326 0.397 View mutations
423 P 1 18 19 0.944 0.767 View mutations
424 D 3 16 19 0.825 0.657 View mutations
425 E 3 16 19 0.793 0.653 View mutations