P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 L 1 18 19 0.948 0.912 View mutations
377 A 0 19 19 0.998 0.970 View mutations
378 R 0 19 19 1.000 0.848 View mutations
379 L 0 19 19 0.995 0.940 View mutations
380 W 0 19 19 1.000 0.949 View mutations
381 G 0 19 19 1.000 1.000 View mutations
382 N 0 19 19 1.000 0.865 View mutations
383 H 0 19 19 1.000 0.891 View mutations
384 K 0 19 19 0.992 0.939 View mutations
385 N 0 19 19 0.999 0.913 View mutations
386 R 0 19 19 1.000 0.902 View mutations
387 T 0 19 19 0.998 0.902 View mutations
388 N 2 17 19 0.902 0.810 View mutations
389 M 1 18 19 0.952 0.928 View mutations
390 T 0 19 19 0.996 0.974 View mutations
391 Y 1 18 19 0.942 0.901 View mutations
392 E 7 12 19 0.682 0.609 View mutations
393 K 1 18 19 0.952 0.878 View mutations
394 M 0 19 19 0.991 0.952 View mutations
395 S 4 15 19 0.780 0.782 View mutations
396 R 1 18 19 0.948 0.869 View mutations
397 A 0 19 19 1.000 0.981 View mutations
398 L 0 19 19 0.996 0.979 View mutations
399 R 1 18 19 0.947 0.919 View mutations
400 H 0 19 19 1.000 0.913 View mutations