P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 I 11 8 19 0.453 0.502 View mutations
177 E 18 1 19 0.149 0.621 View mutations
178 L 19 0 19 0.041 0.683 View mutations
179 L 12 7 19 0.392 0.545 View mutations
180 H 15 4 19 0.259 0.633 View mutations
181 R 17 2 19 0.154 0.702 View mutations
182 S 18 1 19 0.064 0.747 View mutations
183 R 5 14 19 0.680 0.339 View mutations
184 S 19 0 19 0.007 0.783 View mutations
185 P 19 0 19 0.030 0.749 View mutations
186 I 18 1 19 0.061 0.850 View mutations
187 T 8 11 19 0.545 0.422 View mutations
188 T 16 3 19 0.180 0.814 View mutations
189 N 18 1 19 0.068 0.880 View mutations
190 H 19 0 19 0.021 0.933 View mutations
191 R 18 1 19 0.080 0.916 View mutations
192 P 19 0 19 0.022 0.963 View mutations
193 S 11 8 19 0.369 0.563 View mutations
194 P 0 19 19 0.982 0.073 View mutations
195 D 15 4 19 0.281 0.762 View mutations
196 P 16 3 19 0.188 0.814 View mutations
197 E 15 4 19 0.211 0.760 View mutations
198 Q 16 3 19 0.225 0.836 View mutations
199 R 18 1 19 0.065 0.923 View mutations
200 P 18 1 19 0.084 0.938 View mutations