P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 E 12 7 19 0.332 0.590 View mutations
227 N 12 7 19 0.355 0.582 View mutations
228 N 14 5 19 0.296 0.661 View mutations
229 H 4 15 19 0.822 0.280 View mutations
230 Q 3 16 19 0.821 0.240 View mutations
231 E 4 15 19 0.812 0.303 View mutations
232 S 7 12 19 0.657 0.387 View mutations
233 Y 4 15 19 0.795 0.313 View mutations
234 P 10 9 19 0.497 0.477 View mutations
235 L 11 8 19 0.476 0.474 View mutations
236 S 17 2 19 0.114 0.649 View mutations
237 V 5 14 19 0.761 0.382 View mutations
238 S 11 8 19 0.443 0.508 View mutations
239 P 8 11 19 0.596 0.427 View mutations
240 M 12 7 19 0.392 0.578 View mutations
241 E 2 17 19 0.816 0.197 View mutations
242 N 15 4 19 0.241 0.684 View mutations
243 N 19 0 19 0.057 0.786 View mutations
244 H 19 0 19 0.022 0.806 View mutations
245 C 16 3 19 0.145 0.764 View mutations
246 P 19 0 19 0.010 0.928 View mutations
247 A 19 0 19 0.021 0.987 View mutations
248 S 11 8 19 0.375 0.571 View mutations
249 S 5 14 19 0.711 0.293 View mutations
250 E 19 0 19 0.019 0.900 View mutations