P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 L 19 0 19 0.038 0.940 View mutations
202 R 19 0 19 0.018 0.938 View mutations
203 S 19 0 19 0.004 0.899 View mutations
204 P 19 0 19 0.005 0.932 View mutations
205 L 18 1 19 0.218 0.922 View mutations
206 D 16 3 19 0.242 0.809 View mutations
207 N 16 3 19 0.252 0.822 View mutations
208 M 16 3 19 0.143 0.832 View mutations
209 I 15 4 19 0.207 0.789 View mutations
210 R 14 5 19 0.226 0.726 View mutations
211 R 14 5 19 0.270 0.715 View mutations
212 L 3 16 19 0.756 0.187 View mutations
213 S 4 15 19 0.642 0.215 View mutations
214 P 1 18 19 0.940 0.079 View mutations
215 A 17 2 19 0.084 0.829 View mutations
216 E 1 18 19 0.895 0.122 View mutations
217 R 18 1 19 0.053 0.909 View mutations
218 A 10 9 19 0.477 0.518 View mutations
219 Q 18 1 19 0.088 0.944 View mutations
220 G 19 0 19 0.023 0.916 View mutations
221 P 19 0 19 0.012 0.926 View mutations
222 R 16 3 19 0.197 0.771 View mutations
223 P 19 0 19 0.040 0.884 View mutations
224 H 18 1 19 0.088 0.856 View mutations
225 Q 16 3 19 0.233 0.746 View mutations