P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 0 18 18 1.000 0.406 View mutations
2 S 4 15 19 0.762 0.350 View mutations
3 S 2 17 19 0.885 0.292 View mutations
4 A 0 19 19 0.940 0.269 View mutations
5 R 19 0 19 0.033 0.589 View mutations
6 F 17 2 19 0.122 0.481 View mutations
7 D 19 0 19 0.062 0.561 View mutations
8 S 19 0 19 0.017 0.551 View mutations
9 S 18 1 19 0.058 0.583 View mutations
10 D 2 17 19 0.876 0.353 View mutations
11 R 19 0 19 0.002 0.573 View mutations
12 S 7 12 19 0.632 0.414 View mutations
13 A 16 3 19 0.151 0.446 View mutations
14 W 0 19 19 0.982 0.413 View mutations
15 Y 18 1 19 0.057 0.433 View mutations
16 M 19 0 19 0.007 0.508 View mutations
17 G 8 11 19 0.514 0.436 View mutations
18 P 7 12 19 0.619 0.434 View mutations
19 V 6 13 19 0.690 0.428 View mutations
20 S 12 7 19 0.436 0.440 View mutations
21 R 0 19 19 1.000 0.483 View mutations
22 Q 10 9 19 0.427 0.453 View mutations
23 E 1 18 19 0.961 0.439 View mutations
24 A 0 19 19 1.000 0.457 View mutations
25 Q 0 19 19 0.999 0.511 View mutations