P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 S 0 19 19 1.000 0.877 View mutations
52 V 0 19 19 1.000 0.839 View mutations
53 S 0 19 19 1.000 0.853 View mutations
54 E 0 19 19 1.000 0.834 View mutations
55 N 14 5 19 0.338 0.396 View mutations
56 S 8 11 19 0.612 0.540 View mutations
57 R 1 18 19 0.947 0.688 View mutations
58 V 1 18 19 0.958 0.775 View mutations
59 S 0 19 19 0.984 0.796 View mutations
60 H 0 19 19 1.000 0.763 View mutations
61 Y 0 19 19 1.000 0.696 View mutations
62 I 0 19 19 1.000 0.662 View mutations
63 I 3 16 19 0.868 0.569 View mutations
64 N 1 18 19 0.959 0.545 View mutations
65 S 2 17 19 0.847 0.512 View mutations
66 L 11 8 19 0.416 0.469 View mutations
67 P 6 13 19 0.623 0.407 View mutations
68 N 10 9 19 0.480 0.460 View mutations
69 R 16 3 19 0.180 0.501 View mutations
70 R 5 14 19 0.656 0.452 View mutations
71 F 2 17 19 0.899 0.552 View mutations
72 K 1 18 19 0.947 0.570 View mutations
73 I 0 19 19 1.000 0.708 View mutations
74 G 0 19 19 1.000 0.783 View mutations
75 D 1 18 19 0.957 0.714 View mutations