P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 T 11 8 19 0.403 0.448 View mutations
27 R 15 4 19 0.245 0.405 View mutations
28 L 0 19 19 0.993 0.626 View mutations
29 Q 0 19 19 0.954 0.526 View mutations
30 G 1 18 19 0.959 0.604 View mutations
31 Q 5 14 19 0.711 0.534 View mutations
32 R 12 7 19 0.385 0.486 View mutations
33 H 0 19 19 1.000 0.655 View mutations
34 G 0 19 19 0.967 0.670 View mutations
35 M 3 16 19 0.843 0.573 View mutations
36 F 1 18 19 0.906 0.672 View mutations
37 L 0 19 19 0.986 0.639 View mutations
38 V 0 19 19 1.000 0.666 View mutations
39 R 0 19 19 1.000 0.622 View mutations
40 D 0 19 19 1.000 0.558 View mutations
41 S 0 19 19 1.000 0.594 View mutations
42 S 11 8 19 0.473 0.420 View mutations
43 T 6 13 19 0.657 0.536 View mutations
44 C 1 18 19 0.950 0.533 View mutations
45 P 0 19 19 1.000 0.645 View mutations
46 G 0 19 19 1.000 0.705 View mutations
47 D 0 19 19 1.000 0.638 View mutations
48 Y 1 18 19 0.959 0.656 View mutations
49 V 0 19 19 1.000 0.773 View mutations
50 L 0 19 19 1.000 0.899 View mutations