P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 0 18 18 0.964 0.536 View mutations
2 Q 12 7 19 0.430 0.440 View mutations
3 Q 1 18 19 0.958 0.368 View mutations
4 P 13 6 19 0.341 0.441 View mutations
5 F 18 1 19 0.082 0.547 View mutations
6 N 16 3 19 0.137 0.472 View mutations
7 Y 19 0 19 0.002 0.521 View mutations
8 P 19 0 19 0.018 0.488 View mutations
9 Y 18 1 19 0.150 0.477 View mutations
10 P 12 7 19 0.362 0.416 View mutations
11 Q 19 0 19 0.058 0.437 View mutations
12 I 3 16 19 0.861 0.417 View mutations
13 Y 11 8 19 0.451 0.451 View mutations
14 W 0 19 19 0.828 0.434 View mutations
15 V 19 0 19 0.046 0.387 View mutations
16 D 19 0 19 0.008 0.469 View mutations
17 S 19 0 19 0.036 0.605 View mutations
18 S 10 9 19 0.491 0.464 View mutations
19 A 5 14 19 0.710 0.397 View mutations
20 S 19 0 19 0.061 0.654 View mutations
21 S 2 17 19 0.867 0.312 View mutations
22 P 14 5 19 0.312 0.522 View mutations
23 W 0 19 19 0.994 0.314 View mutations
24 A 6 13 19 0.665 0.396 View mutations
25 P 2 17 19 0.868 0.314 View mutations