P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 14 5 19 0.309 0.705 View mutations
52 P 16 3 19 0.175 0.809 View mutations
53 P 16 3 19 0.187 0.833 View mutations
54 L 15 4 19 0.322 0.777 View mutations
55 P 14 5 19 0.288 0.737 View mutations
56 P 16 3 19 0.153 0.821 View mutations
57 P 19 0 19 0.001 0.958 View mutations
58 P 18 1 19 0.055 0.935 View mutations
59 P 18 1 19 0.075 0.904 View mutations
60 P 15 4 19 0.214 0.769 View mutations
61 P 11 8 19 0.457 0.577 View mutations
62 P 16 3 19 0.155 0.805 View mutations
63 L 17 2 19 0.102 0.821 View mutations
64 P 15 4 19 0.233 0.741 View mutations
65 P 19 0 19 0.025 0.905 View mutations
66 L 19 0 19 0.022 0.870 View mutations
67 P 18 1 19 0.094 0.812 View mutations
68 L 18 1 19 0.109 0.800 View mutations
69 P 17 2 19 0.119 0.737 View mutations
70 P 19 0 19 0.034 0.779 View mutations
71 L 17 2 19 0.145 0.718 View mutations
72 K 19 0 19 0.043 0.728 View mutations
73 K 15 4 19 0.261 0.645 View mutations
74 R 17 2 19 0.134 0.666 View mutations
75 G 16 3 19 0.154 0.642 View mutations