P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 P 11 8 19 0.438 0.473 View mutations
27 G 17 2 19 0.160 0.510 View mutations
28 T 18 1 19 0.201 0.639 View mutations
29 V 10 9 19 0.432 0.466 View mutations
30 L 12 7 19 0.329 0.500 View mutations
31 P 10 9 19 0.497 0.470 View mutations
32 C 12 7 19 0.386 0.519 View mutations
33 P 1 18 19 0.921 0.297 View mutations
34 T 13 6 19 0.292 0.564 View mutations
35 S 8 11 19 0.528 0.428 View mutations
36 V 19 0 19 0.044 0.652 View mutations
37 P 13 6 19 0.380 0.567 View mutations
38 R 9 10 19 0.561 0.453 View mutations
39 R 4 15 19 0.735 0.336 View mutations
40 P 6 13 19 0.728 0.381 View mutations
41 G 10 9 19 0.469 0.469 View mutations
42 Q 18 1 19 0.065 0.693 View mutations
43 R 18 1 19 0.065 0.743 View mutations
44 R 12 7 19 0.344 0.566 View mutations
45 P 12 7 19 0.378 0.589 View mutations
46 P 17 2 19 0.135 0.873 View mutations
47 P 16 3 19 0.152 0.821 View mutations
48 P 17 2 19 0.160 0.861 View mutations
49 P 14 5 19 0.271 0.712 View mutations
50 P 9 10 19 0.515 0.473 View mutations