P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 G 17 2 19 0.162 0.735 View mutations
127 P 4 15 19 0.752 0.296 View mutations
128 P 4 15 19 0.779 0.297 View mutations
129 P 10 9 19 0.477 0.479 View mutations
130 G 4 15 19 0.783 0.336 View mutations
131 Y 0 19 19 0.997 0.279 View mutations
132 G 8 11 19 0.556 0.431 View mutations
133 C 0 19 19 0.994 0.304 View mutations
134 A 8 11 19 0.558 0.428 View mutations
135 A 15 4 19 0.234 0.606 View mutations
136 A 14 5 19 0.287 0.582 View mutations
137 G 14 5 19 0.341 0.525 View mutations
138 Y 9 10 19 0.479 0.438 View mutations
139 L 15 4 19 0.281 0.500 View mutations
140 D 4 15 19 0.690 0.423 View mutations
141 G 19 0 19 0.009 0.519 View mutations
142 R 19 0 19 0.000 0.484 View mutations
143 L 19 0 19 0.000 0.477 View mutations
144 E 19 0 19 0.006 0.479 View mutations
145 P 19 0 19 0.000 0.531 View mutations
146 L 19 0 19 0.007 0.590 View mutations
147 Y 18 1 19 0.153 0.539 View mutations
148 E 19 0 19 0.015 0.499 View mutations
149 R 19 0 19 0.000 0.611 View mutations
150 V 19 0 19 0.000 0.632 View mutations