P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 19 0 19 0.073 0.585 View mutations
152 A 4 15 19 0.714 0.347 View mutations
153 P 16 3 19 0.197 0.555 View mutations
154 A 15 4 19 0.182 0.512 View mutations
155 L 4 15 19 0.819 0.404 View mutations
156 R 6 13 19 0.705 0.438 View mutations
157 P 0 19 19 0.998 0.488 View mutations
158 L 1 18 19 0.938 0.440 View mutations
159 V 3 16 19 0.819 0.459 View mutations
160 I 1 18 19 0.952 0.451 View mutations
161 K 0 19 19 1.000 0.501 View mutations
162 Q 0 19 19 1.000 0.504 View mutations
163 E 0 19 19 1.000 0.490 View mutations
164 P 0 19 19 0.999 0.491 View mutations
165 R 13 6 19 0.418 0.448 View mutations
166 E 1 18 19 0.952 0.395 View mutations
167 E 7 12 19 0.570 0.418 View mutations
168 D 12 7 19 0.372 0.494 View mutations
169 E 19 0 19 0.026 0.606 View mutations
170 A 18 1 19 0.059 0.715 View mutations
171 K 15 4 19 0.212 0.637 View mutations
172 Q 19 0 19 0.018 0.754 View mutations
173 L 19 0 19 0.003 0.760 View mutations
174 A 19 0 19 0.001 0.718 View mutations
175 L 19 0 19 0.012 0.672 View mutations