P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 T 15 4 19 0.262 0.498 View mutations
77 K 18 1 19 0.084 0.487 View mutations
78 L 1 18 19 0.965 0.571 View mutations
79 V 3 16 19 0.870 0.604 View mutations
80 Y 1 18 19 0.927 0.546 View mutations
81 Q 1 18 19 0.947 0.646 View mutations
82 N 1 18 19 0.955 0.708 View mutations
83 I 1 18 19 0.937 0.686 View mutations
84 F 15 4 19 0.241 0.472 View mutations
85 T 15 4 19 0.240 0.454 View mutations
86 A 18 1 19 0.094 0.353 View mutations
87 M 2 17 19 0.873 0.630 View mutations
88 Q 17 2 19 0.096 0.447 View mutations
89 A 19 0 19 0.009 0.430 View mutations
90 M 19 0 19 0.015 0.262 View mutations
91 I 18 1 19 0.063 0.490 View mutations
92 R 19 0 19 0.000 0.416 View mutations
93 A 12 7 19 0.423 0.445 View mutations
94 M 19 0 19 0.020 0.328 View mutations
95 D 19 0 19 0.081 0.441 View mutations
96 T 15 4 19 0.285 0.425 View mutations
97 L 17 2 19 0.219 0.343 View mutations
98 K 19 0 19 0.021 0.425 View mutations
99 I 0 19 19 0.968 0.662 View mutations
100 P 11 8 19 0.373 0.440 View mutations