P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 N 19 0 19 0.001 0.670 View mutations
127 P 19 0 19 0.039 0.759 View mutations
128 Y 8 11 19 0.513 0.432 View mutations
129 V 19 0 19 0.007 0.564 View mutations
130 D 17 2 19 0.172 0.590 View mutations
131 A 9 10 19 0.562 0.444 View mutations
132 I 4 15 19 0.782 0.584 View mutations
133 K 18 1 19 0.040 0.541 View mutations
134 S 18 1 19 0.052 0.622 View mutations
135 L 19 0 19 0.008 0.347 View mutations
136 W 0 19 19 0.910 0.702 View mutations
137 N 18 1 19 0.085 0.417 View mutations
138 D 16 3 19 0.308 0.456 View mutations
139 P 19 0 19 0.015 0.456 View mutations
140 G 2 17 19 0.860 0.574 View mutations
141 I 10 9 19 0.443 0.489 View mutations
142 Q 19 0 19 0.002 0.373 View mutations
143 E 19 0 19 0.016 0.514 View mutations
144 C 6 13 19 0.687 0.531 View mutations
145 Y 19 0 19 0.028 0.416 View mutations
146 D 19 0 19 0.000 0.359 View mutations
147 R 0 19 19 0.964 0.626 View mutations
148 R 19 0 19 0.000 0.379 View mutations
149 R 19 0 19 0.002 0.354 View mutations
150 E 19 0 19 0.002 0.205 View mutations