P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 E 17 2 19 0.084 0.822 View mutations
27 P 19 0 19 0.024 0.937 View mutations
28 E 19 0 19 0.036 0.916 View mutations
29 G 19 0 19 0.003 0.961 View mutations
30 P 19 0 19 0.005 0.972 View mutations
31 P 19 0 19 0.002 0.978 View mutations
32 P 19 0 19 0.002 0.938 View mutations
33 S 19 0 19 0.062 0.958 View mutations
34 P 19 0 19 0.039 0.965 View mutations
35 G 19 0 19 0.017 0.965 View mutations
36 K 19 0 19 0.002 0.940 View mutations
37 G 18 1 19 0.031 0.888 View mutations
38 G 19 0 19 0.002 0.961 View mutations
39 G 19 0 19 0.005 0.983 View mutations
40 G 19 0 19 0.028 1.000 View mutations
41 G 19 0 19 0.004 0.992 View mutations
42 G 19 0 19 0.001 0.952 View mutations
43 G 19 0 19 0.001 0.929 View mutations
44 T 15 4 19 0.223 0.724 View mutations
45 A 14 5 19 0.279 0.656 View mutations
46 P 19 0 19 0.005 0.823 View mutations
47 E 8 11 19 0.598 0.428 View mutations
48 K 17 2 19 0.118 0.632 View mutations
49 P 10 9 19 0.505 0.483 View mutations
50 D 0 19 19 0.990 0.337 View mutations