P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 0 19 19 0.893 0.387 View mutations
52 A 4 15 19 0.793 0.433 View mutations
53 Q 0 19 19 0.994 0.497 View mutations
54 K 1 18 19 0.859 0.556 View mutations
55 P 0 19 19 0.983 0.627 View mutations
56 P 0 19 19 0.995 0.612 View mutations
57 Y 0 19 19 1.000 0.621 View mutations
58 S 0 19 19 1.000 0.700 View mutations
59 Y 0 19 19 1.000 0.668 View mutations
60 V 0 19 19 1.000 0.687 View mutations
61 A 0 19 19 1.000 0.704 View mutations
62 L 0 19 19 1.000 0.684 View mutations
63 I 0 19 19 1.000 0.678 View mutations
64 A 0 19 19 1.000 0.677 View mutations
65 M 0 19 19 1.000 0.668 View mutations
66 A 0 19 19 0.992 0.691 View mutations
67 I 0 19 19 0.988 0.653 View mutations
68 R 0 19 19 0.988 0.586 View mutations
69 E 1 18 19 0.958 0.618 View mutations
70 S 0 19 19 0.995 0.665 View mutations
71 A 0 19 19 0.998 0.571 View mutations
72 E 0 19 19 1.000 0.640 View mutations
73 K 0 19 19 1.000 0.653 View mutations
74 R 0 19 19 1.000 0.697 View mutations
75 L 0 19 19 1.000 0.720 View mutations