P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 C 19 0 19 0.054 0.745 View mutations
177 G 19 0 19 0.034 0.719 View mutations
178 V 19 0 19 0.052 0.742 View mutations
179 A 19 0 19 0.002 0.756 View mutations
180 G 19 0 19 0.014 0.781 View mutations
181 A 19 0 19 0.000 0.801 View mutations
182 G 19 0 19 0.002 0.843 View mutations
183 A 19 0 19 0.017 0.780 View mutations
184 D 19 0 19 0.028 0.553 View mutations
185 G 19 0 19 0.106 0.607 View mutations
186 Y 19 0 19 0.004 0.490 View mutations
187 G 10 9 19 0.558 0.434 View mutations
188 Y 17 2 19 0.132 0.431 View mutations
189 L 8 11 19 0.593 0.435 View mutations
190 A 11 8 19 0.464 0.453 View mutations
191 P 0 19 19 0.883 0.422 View mutations
192 P 6 13 19 0.683 0.443 View mutations
193 K 18 1 19 0.247 0.394 View mutations
194 Y 12 7 19 0.334 0.416 View mutations
195 L 18 1 19 0.157 0.381 View mutations
196 Q 11 8 19 0.387 0.422 View mutations
197 S 16 3 19 0.207 0.464 View mutations
198 G 12 7 19 0.416 0.432 View mutations
199 F 18 1 19 0.052 0.457 View mutations
200 L 15 4 19 0.260 0.466 View mutations