P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 N 0 19 19 0.879 0.924 View mutations
127 Y 0 19 19 0.990 0.928 View mutations
128 W 0 19 19 0.954 0.951 View mutations
129 T 1 18 19 0.851 0.883 View mutations
130 L 0 19 19 0.977 0.956 View mutations
131 D 8 11 19 0.613 0.564 View mutations
132 P 3 16 19 0.773 0.790 View mutations
133 A 1 18 19 0.948 0.780 View mutations
134 C 0 19 19 0.983 0.907 View mutations
135 E 0 19 19 0.876 0.923 View mutations
136 D 0 19 19 0.909 0.946 View mutations
137 M 0 19 19 0.955 0.916 View mutations
138 F 1 18 19 0.834 0.914 View mutations
139 E 0 19 19 0.868 0.944 View mutations
140 K 1 18 19 0.849 0.763 View mutations
141 G 0 19 19 0.958 0.953 View mutations
142 N 13 6 19 0.354 0.357 View mutations
143 Y 7 12 19 0.591 0.615 View mutations
144 R 15 4 19 0.236 0.292 View mutations
145 R 10 9 19 0.442 0.481 View mutations
146 R 12 7 19 0.353 0.404 View mutations
147 R 11 8 19 0.412 0.447 View mutations
148 R 15 4 19 0.324 0.321 View mutations
149 M 19 0 19 0.131 0.202 View mutations
150 K 16 3 19 0.256 0.335 View mutations