P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.648 View mutations
2 V 19 0 19 0.016 0.864 View mutations
3 A 11 8 19 0.460 0.538 View mutations
4 E 19 0 19 0.016 0.849 View mutations
5 R 19 0 19 0.001 0.869 View mutations
6 S 19 0 19 0.003 0.864 View mutations
7 P 19 0 19 0.000 0.906 View mutations
8 A 19 0 19 0.002 0.919 View mutations
9 R 19 0 19 0.001 0.913 View mutations
10 S 19 0 19 0.001 0.929 View mutations
11 P 19 0 19 0.000 0.954 View mutations
12 G 19 0 19 0.020 0.952 View mutations
13 S 19 0 19 0.002 0.941 View mutations
14 W 19 0 19 0.008 0.952 View mutations
15 L 19 0 19 0.000 0.957 View mutations
16 F 19 0 19 0.001 0.973 View mutations
17 P 19 0 19 0.001 0.989 View mutations
18 G 19 0 19 0.001 1.000 View mutations
19 L 19 0 19 0.001 0.973 View mutations
20 W 19 0 19 0.000 0.970 View mutations
21 L 19 0 19 0.003 0.988 View mutations
22 L 19 0 19 0.000 0.937 View mutations
23 V 19 0 19 0.001 0.909 View mutations
24 L 19 0 19 0.027 0.946 View mutations
25 S 19 0 19 0.002 0.915 View mutations