P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 G 19 0 19 0.001 0.915 View mutations
27 P 19 0 19 0.000 0.944 View mutations
28 G 19 0 19 0.000 0.947 View mutations
29 G 19 0 19 0.001 0.929 View mutations
30 L 19 0 19 0.000 0.954 View mutations
31 L 19 0 19 0.000 0.967 View mutations
32 R 19 0 19 0.000 0.930 View mutations
33 A 19 0 19 0.000 0.870 View mutations
34 Q 19 0 19 0.000 0.832 View mutations
35 E 19 0 19 0.047 0.683 View mutations
36 Q 19 0 19 0.003 0.677 View mutations
37 P 19 0 19 0.001 0.557 View mutations
38 S 10 9 19 0.540 0.428 View mutations
39 C 0 19 19 1.000 0.504 View mutations
40 R 16 3 19 0.175 0.431 View mutations
41 R 11 8 19 0.478 0.491 View mutations
42 A 19 0 19 0.002 0.423 View mutations
43 F 17 2 19 0.101 0.435 View mutations
44 D 0 19 19 1.000 0.562 View mutations
45 L 3 16 19 0.817 0.532 View mutations
46 Y 1 18 19 0.947 0.568 View mutations
47 F 1 18 19 0.904 0.599 View mutations
48 V 2 17 19 0.875 0.593 View mutations
49 L 1 18 19 0.966 0.618 View mutations
50 D 1 18 19 0.948 0.567 View mutations