P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 P 0 19 19 0.981 0.737 View mutations
77 E 18 1 19 0.051 0.489 View mutations
78 M 0 19 19 0.993 0.606 View mutations
79 R 2 17 19 0.877 0.671 View mutations
80 L 3 16 19 0.844 0.595 View mutations
81 S 0 19 19 0.989 0.777 View mutations
82 F 0 19 19 0.990 0.746 View mutations
83 I 1 18 19 0.970 0.772 View mutations
84 V 10 9 19 0.460 0.491 View mutations
85 F 0 19 19 1.000 0.798 View mutations
86 S 10 9 19 0.424 0.488 View mutations
87 S 4 15 19 0.744 0.560 View mutations
88 Q 13 6 19 0.328 0.498 View mutations
89 A 11 8 19 0.444 0.493 View mutations
90 T 19 0 19 0.000 0.385 View mutations
91 I 16 3 19 0.157 0.461 View mutations
92 I 19 0 19 0.000 0.392 View mutations
93 L 7 12 19 0.636 0.555 View mutations
94 P 19 0 19 0.131 0.404 View mutations
95 L 3 16 19 0.808 0.650 View mutations
96 T 3 16 19 0.843 0.629 View mutations
97 G 9 10 19 0.495 0.508 View mutations
98 D 18 1 19 0.055 0.364 View mutations
99 R 2 17 19 0.868 0.595 View mutations
100 G 11 8 19 0.454 0.439 View mutations