P61244 (MAX)

Overview
Predicted structure (AF):
AF-P61244-F1-model_v4
Uniprot entry:
P61244
Gene:
MAX
Protein length:
160 residues
Mutations found:
3039
Benign based on D2Deep prediction:
1752 out of 3039 mutations
Pathogenic based on D2Deep prediction:
1287 out of 3039 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3039 mutations across 160 unique positions. There are 1752 benign and 1287 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 11 7 18 0.443 0.454 View mutations
2 S 3 16 19 0.764 0.332 View mutations
3 D 1 18 19 0.951 0.290 View mutations
4 N 10 9 19 0.554 0.480 View mutations
5 D 18 1 19 0.090 0.629 View mutations
6 D 12 7 19 0.409 0.515 View mutations
7 I 19 0 19 0.004 0.772 View mutations
8 E 19 0 19 0.010 0.758 View mutations
9 V 18 1 19 0.085 0.669 View mutations
10 E 15 4 19 0.265 0.634 View mutations
11 S 19 0 19 0.003 0.839 View mutations
12 D 12 7 19 0.403 0.583 View mutations
13 E 19 0 19 0.018 0.988 View mutations
14 E 19 0 19 0.015 0.973 View mutations
15 Q 19 0 19 0.002 0.951 View mutations
16 P 19 0 19 0.004 0.989 View mutations
17 R 19 0 19 0.012 0.984 View mutations
18 F 18 1 19 0.121 0.906 View mutations
19 Q 19 0 19 0.028 0.996 View mutations
20 S 18 1 19 0.097 0.920 View mutations
21 A 15 4 19 0.275 0.682 View mutations
22 A 11 8 19 0.415 0.458 View mutations
23 D 2 17 19 0.871 0.404 View mutations
24 K 0 19 19 0.998 0.481 View mutations
25 R 0 19 19 1.000 0.503 View mutations