P61244 (MAX)

Overview
Predicted structure (AF):
AF-P61244-F1-model_v4
Uniprot entry:
P61244
Gene:
MAX
Protein length:
160 residues
Mutations found:
3039
Benign based on D2Deep prediction:
1752 out of 3039 mutations
Pathogenic based on D2Deep prediction:
1287 out of 3039 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3039 mutations across 160 unique positions. There are 1752 benign and 1287 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 A 6 13 19 0.675 0.577 View mutations
27 H 9 10 19 0.569 0.507 View mutations
28 H 3 16 19 0.818 0.678 View mutations
29 N 4 15 19 0.776 0.620 View mutations
30 A 0 19 19 0.997 0.787 View mutations
31 L 1 18 19 0.828 0.700 View mutations
32 E 1 18 19 0.962 0.764 View mutations
33 R 0 19 19 1.000 0.689 View mutations
34 K 1 18 19 0.962 0.638 View mutations
35 R 0 19 19 1.000 0.726 View mutations
36 R 2 17 19 0.912 0.688 View mutations
37 D 0 19 19 1.000 0.803 View mutations
38 H 0 19 19 1.000 0.726 View mutations
39 I 0 19 19 1.000 0.767 View mutations
40 K 0 19 19 1.000 0.655 View mutations
41 D 0 19 19 0.988 0.672 View mutations
42 S 2 17 19 0.897 0.641 View mutations
43 F 6 13 19 0.716 0.544 View mutations
44 H 6 13 19 0.629 0.446 View mutations
45 S 1 18 19 0.920 0.585 View mutations
46 L 0 19 19 0.957 0.696 View mutations
47 R 1 18 19 0.904 0.593 View mutations
48 D 1 18 19 0.948 0.628 View mutations
49 S 9 10 19 0.525 0.503 View mutations
50 V 2 17 19 0.902 0.641 View mutations