P61244 (MAX)

Overview
Predicted structure (AF):
AF-P61244-F1-model_v4
Uniprot entry:
P61244
Gene:
MAX
Protein length:
160 residues
Mutations found:
3039
Benign based on D2Deep prediction:
1752 out of 3039 mutations
Pathogenic based on D2Deep prediction:
1287 out of 3039 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3039 mutations across 160 unique positions. There are 1752 benign and 1287 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 0 19 19 1.000 0.677 View mutations
52 S 3 16 19 0.854 0.545 View mutations
53 L 0 19 19 1.000 0.630 View mutations
54 Q 6 13 19 0.686 0.523 View mutations
55 G 10 9 19 0.535 0.491 View mutations
56 E 0 19 19 0.947 0.704 View mutations
57 K 0 19 19 1.000 0.728 View mutations
58 A 3 16 19 0.844 0.679 View mutations
59 S 1 18 19 0.938 0.777 View mutations
60 R 0 19 19 1.000 0.748 View mutations
61 A 0 19 19 1.000 0.898 View mutations
62 Q 0 19 19 1.000 0.734 View mutations
63 I 9 10 19 0.539 0.526 View mutations
64 L 2 17 19 0.901 0.827 View mutations
65 D 5 14 19 0.711 0.611 View mutations
66 K 4 15 19 0.771 0.640 View mutations
67 A 1 18 19 0.938 0.823 View mutations
68 T 1 18 19 0.929 0.787 View mutations
69 E 6 13 19 0.650 0.589 View mutations
70 Y 3 16 19 0.834 0.686 View mutations
71 I 0 19 19 1.000 0.920 View mutations
72 Q 1 18 19 0.916 0.555 View mutations
73 Y 6 13 19 0.676 0.546 View mutations
74 M 1 18 19 0.940 0.755 View mutations
75 R 1 18 19 0.946 0.668 View mutations