P61769 (B2M)

Overview
Predicted structure (AF):
AF-P61769-F1-model_v4
Uniprot entry:
P61769
Gene:
B2M
Protein length:
119 residues
Mutations found:
2260
Benign based on D2Deep prediction:
1295 out of 2260 mutations
Pathogenic based on D2Deep prediction:
965 out of 2260 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 2260 mutations across 119 unique positions. There are 1295 benign and 965 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.024 0.691 View mutations
2 S 19 0 19 0.001 0.903 View mutations
3 R 13 6 19 0.290 0.637 View mutations
4 S 19 0 19 0.008 0.947 View mutations
5 V 18 1 19 0.042 0.874 View mutations
6 A 19 0 19 0.004 0.917 View mutations
7 L 19 0 19 0.035 1.000 View mutations
8 A 19 0 19 0.002 0.932 View mutations
9 V 19 0 19 0.031 0.889 View mutations
10 L 16 3 19 0.165 0.785 View mutations
11 A 19 0 19 0.001 0.881 View mutations
12 L 18 1 19 0.074 0.832 View mutations
13 L 19 0 19 0.004 0.881 View mutations
14 S 19 0 19 0.008 0.903 View mutations
15 L 19 0 19 0.006 0.897 View mutations
16 S 19 0 19 0.009 0.978 View mutations
17 G 19 0 19 0.007 0.917 View mutations
18 L 19 0 19 0.034 0.989 View mutations
19 E 16 3 19 0.117 0.792 View mutations
20 A 13 6 19 0.257 0.621 View mutations
21 I 18 1 19 0.130 0.846 View mutations
22 Q 18 1 19 0.073 0.778 View mutations
23 R 8 11 19 0.583 0.429 View mutations
24 T 11 8 19 0.405 0.488 View mutations
25 P 0 19 19 1.000 0.582 View mutations