P61769 (B2M)

Overview
Predicted structure (AF):
AF-P61769-F1-model_v4
Uniprot entry:
P61769
Gene:
B2M
Protein length:
119 residues
Mutations found:
2260
Benign based on D2Deep prediction:
1295 out of 2260 mutations
Pathogenic based on D2Deep prediction:
965 out of 2260 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2260 mutations across 119 unique positions. There are 1295 benign and 965 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 H 0 19 19 1.000 0.833 View mutations
52 P 0 19 19 1.000 0.842 View mutations
53 S 1 18 19 0.944 0.827 View mutations
54 D 1 18 19 0.953 0.541 View mutations
55 I 7 12 19 0.619 0.583 View mutations
56 E 16 3 19 0.201 0.403 View mutations
57 V 1 18 19 0.946 0.695 View mutations
58 D 19 0 19 0.089 0.443 View mutations
59 L 3 16 19 0.807 0.671 View mutations
60 L 4 15 19 0.772 0.455 View mutations
61 K 1 18 19 0.952 0.645 View mutations
62 N 0 19 19 1.000 0.755 View mutations
63 G 9 10 19 0.517 0.512 View mutations
64 E 13 6 19 0.385 0.481 View mutations
65 R 14 5 19 0.293 0.461 View mutations
66 I 10 9 19 0.465 0.422 View mutations
67 E 9 10 19 0.420 0.443 View mutations
68 K 16 3 19 0.184 0.578 View mutations
69 V 19 0 19 0.086 0.474 View mutations
70 E 12 7 19 0.347 0.489 View mutations
71 H 9 10 19 0.514 0.431 View mutations
72 S 6 13 19 0.670 0.586 View mutations
73 D 0 19 19 0.999 0.879 View mutations
74 L 2 17 19 0.910 0.879 View mutations
75 S 3 16 19 0.854 0.714 View mutations