P61769 (B2M)

Overview
Predicted structure (AF):
AF-P61769-F1-model_v4
Uniprot entry:
P61769
Gene:
B2M
Protein length:
119 residues
Mutations found:
2260
Benign based on D2Deep prediction:
1295 out of 2260 mutations
Pathogenic based on D2Deep prediction:
965 out of 2260 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 2260 mutations across 119 unique positions. There are 1295 benign and 965 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 K 18 1 19 0.081 0.463 View mutations
27 I 18 1 19 0.109 0.324 View mutations
28 Q 17 2 19 0.147 0.358 View mutations
29 V 2 17 19 0.812 0.751 View mutations
30 Y 5 14 19 0.695 0.659 View mutations
31 S 7 12 19 0.564 0.561 View mutations
32 R 16 3 19 0.157 0.299 View mutations
33 H 2 17 19 0.868 0.577 View mutations
34 P 2 17 19 0.874 0.667 View mutations
35 A 9 10 19 0.543 0.509 View mutations
36 E 17 2 19 0.184 0.422 View mutations
37 N 18 1 19 0.085 0.412 View mutations
38 G 0 19 19 0.971 0.716 View mutations
39 K 4 15 19 0.784 0.514 View mutations
40 S 17 2 19 0.163 0.493 View mutations
41 N 0 19 19 1.000 0.718 View mutations
42 F 15 4 19 0.288 0.476 View mutations
43 L 16 3 19 0.167 0.323 View mutations
44 N 8 11 19 0.604 0.536 View mutations
45 C 0 19 19 1.000 1.000 View mutations
46 Y 1 18 19 0.947 0.840 View mutations
47 V 1 18 19 0.951 0.897 View mutations
48 S 11 8 19 0.499 0.450 View mutations
49 G 0 19 19 1.000 0.784 View mutations
50 F 0 19 19 1.000 0.937 View mutations