P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.007 0.630 View mutations
2 Q 15 4 19 0.193 0.718 View mutations
3 A 10 9 19 0.516 0.526 View mutations
4 I 9 10 19 0.516 0.454 View mutations
5 K 1 18 19 0.961 0.424 View mutations
6 C 18 1 19 0.033 0.469 View mutations
7 V 17 2 19 0.109 0.376 View mutations
8 V 19 0 19 0.023 0.402 View mutations
9 V 7 12 19 0.657 0.517 View mutations
10 G 7 12 19 0.631 0.534 View mutations
11 D 1 18 19 0.872 0.573 View mutations
12 G 2 17 19 0.938 0.511 View mutations
13 A 5 14 19 0.698 0.416 View mutations
14 V 0 19 19 0.985 0.549 View mutations
15 G 15 4 19 0.238 0.389 View mutations
16 K 19 0 19 0.000 0.372 View mutations
17 T 1 18 19 0.963 0.486 View mutations
18 C 4 15 19 0.777 0.365 View mutations
19 L 12 7 19 0.364 0.456 View mutations
20 L 18 1 19 0.107 0.503 View mutations
21 I 1 18 19 0.912 0.237 View mutations
22 S 18 1 19 0.055 0.644 View mutations
23 Y 0 19 19 0.905 0.240 View mutations
24 T 1 18 19 0.903 0.322 View mutations
25 T 3 16 19 0.859 0.313 View mutations