P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 V 2 17 19 0.891 0.323 View mutations
52 N 6 13 19 0.698 0.400 View mutations
53 L 0 19 19 1.000 0.529 View mutations
54 G 4 15 19 0.820 0.411 View mutations
55 L 19 0 19 0.054 0.272 View mutations
56 W 1 18 19 0.938 0.605 View mutations
57 D 0 19 19 1.000 0.888 View mutations
58 T 4 15 19 0.772 0.776 View mutations
59 A 2 17 19 0.865 0.887 View mutations
60 G 0 19 19 0.997 1.000 View mutations
61 Q 0 19 19 1.000 0.738 View mutations
62 E 0 19 19 1.000 0.727 View mutations
63 D 5 14 19 0.739 0.566 View mutations
64 Y 1 18 19 0.937 0.676 View mutations
65 D 2 17 19 0.901 0.656 View mutations
66 R 0 19 19 0.949 0.673 View mutations
67 L 4 15 19 0.771 0.664 View mutations
68 R 2 17 19 0.901 0.714 View mutations
69 P 14 5 19 0.232 0.431 View mutations
70 L 4 15 19 0.736 0.674 View mutations
71 S 0 19 19 0.961 0.741 View mutations
72 Y 0 19 19 1.000 0.751 View mutations
73 P 1 18 19 0.904 0.641 View mutations
74 Q 3 16 19 0.798 0.514 View mutations
75 T 2 17 19 0.877 0.543 View mutations