P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 N 15 4 19 0.258 0.532 View mutations
27 A 18 1 19 0.083 0.645 View mutations
28 F 19 0 19 0.023 0.542 View mutations
29 P 2 17 19 0.928 0.445 View mutations
30 G 9 10 19 0.510 0.450 View mutations
31 E 16 3 19 0.250 0.436 View mutations
32 Y 9 10 19 0.483 0.501 View mutations
33 I 2 17 19 0.882 0.400 View mutations
34 P 11 8 19 0.412 0.491 View mutations
35 T 0 19 19 0.981 0.637 View mutations
36 V 9 10 19 0.550 0.503 View mutations
37 F 16 3 19 0.198 0.387 View mutations
38 D 0 19 19 0.999 0.452 View mutations
39 N 1 18 19 0.951 0.411 View mutations
40 Y 4 15 19 0.728 0.394 View mutations
41 S 2 17 19 0.906 0.332 View mutations
42 A 14 5 19 0.338 0.494 View mutations
43 N 19 0 19 0.001 0.619 View mutations
44 V 3 16 19 0.751 0.435 View mutations
45 M 3 16 19 0.773 0.331 View mutations
46 V 10 9 19 0.441 0.443 View mutations
47 D 17 2 19 0.175 0.538 View mutations
48 G 11 8 19 0.427 0.435 View mutations
49 K 9 10 19 0.547 0.452 View mutations
50 P 5 14 19 0.700 0.376 View mutations