P84243 (P84243)

Overview
Predicted structure (AF):
AF-P84243-F1-model_v4
Uniprot entry:
P84243
Gene:
P84243
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1722 out of 2583 mutations
Pathogenic based on D2Deep prediction:
861 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1722 benign and 861 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.375 View mutations
2 A 19 0 19 0.037 0.721 View mutations
3 R 2 17 19 0.809 0.225 View mutations
4 T 15 4 19 0.176 0.624 View mutations
5 K 19 0 19 0.013 0.712 View mutations
6 Q 19 0 19 0.006 0.730 View mutations
7 T 19 0 19 0.000 0.859 View mutations
8 A 19 0 19 0.000 0.814 View mutations
9 R 19 0 19 0.007 0.805 View mutations
10 K 19 0 19 0.001 0.753 View mutations
11 S 19 0 19 0.000 0.832 View mutations
12 T 18 1 19 0.087 0.810 View mutations
13 G 19 0 19 0.003 0.838 View mutations
14 G 12 7 19 0.373 0.546 View mutations
15 K 19 0 19 0.006 0.844 View mutations
16 A 19 0 19 0.000 0.850 View mutations
17 P 12 7 19 0.376 0.547 View mutations
18 R 16 3 19 0.124 0.735 View mutations
19 K 17 2 19 0.166 0.809 View mutations
20 Q 19 0 19 0.000 0.970 View mutations
21 L 8 11 19 0.531 0.425 View mutations
22 A 19 0 19 0.001 0.887 View mutations
23 T 19 0 19 0.025 0.893 View mutations
24 K 19 0 19 0.011 0.915 View mutations
25 A 17 2 19 0.192 0.813 View mutations