P84243 (P84243)

Overview
Predicted structure (AF):
AF-P84243-F1-model_v4
Uniprot entry:
P84243
Gene:
P84243
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1722 out of 2583 mutations
Pathogenic based on D2Deep prediction:
861 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 2583 mutations across 136 unique positions. There are 1722 benign and 861 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 A 19 0 19 0.001 0.936 View mutations
27 R 19 0 19 0.008 0.928 View mutations
28 K 12 7 19 0.431 0.595 View mutations
29 S 18 1 19 0.105 0.947 View mutations
30 A 19 0 19 0.054 0.864 View mutations
31 P 19 0 19 0.000 0.729 View mutations
32 S 19 0 19 0.001 0.866 View mutations
33 T 16 3 19 0.171 0.674 View mutations
34 G 19 0 19 0.000 0.764 View mutations
35 G 11 8 19 0.455 0.513 View mutations
36 V 19 0 19 0.002 0.747 View mutations
37 K 19 0 19 0.000 0.837 View mutations
38 K 10 9 19 0.456 0.474 View mutations
39 P 3 16 19 0.824 0.390 View mutations
40 H 19 0 19 0.071 0.443 View mutations
41 R 15 4 19 0.222 0.494 View mutations
42 Y 17 2 19 0.090 0.449 View mutations
43 R 19 0 19 0.000 0.394 View mutations
44 P 12 7 19 0.337 0.417 View mutations
45 G 3 16 19 0.847 0.679 View mutations
46 T 4 15 19 0.745 0.573 View mutations
47 V 11 8 19 0.479 0.491 View mutations
48 A 11 8 19 0.455 0.453 View mutations
49 L 1 18 19 0.935 0.847 View mutations
50 R 0 19 19 0.999 0.574 View mutations