P84243 (P84243)

Overview
Predicted structure (AF):
AF-P84243-F1-model_v4
Uniprot entry:
P84243
Gene:
P84243
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1722 out of 2583 mutations
Pathogenic based on D2Deep prediction:
861 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1722 benign and 861 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 0 19 19 1.000 0.728 View mutations
52 I 1 18 19 0.934 0.947 View mutations
53 R 0 19 19 1.000 0.774 View mutations
54 R 15 4 19 0.217 0.460 View mutations
55 Y 19 0 19 0.000 0.274 View mutations
56 Q 9 10 19 0.539 0.520 View mutations
57 K 4 15 19 0.808 0.539 View mutations
58 S 17 2 19 0.097 0.419 View mutations
59 T 19 0 19 0.010 0.283 View mutations
60 E 19 0 19 0.101 0.470 View mutations
61 L 5 14 19 0.734 0.603 View mutations
62 L 0 19 19 0.949 0.768 View mutations
63 I 19 0 19 0.045 0.260 View mutations
64 R 18 1 19 0.066 0.464 View mutations
65 K 14 5 19 0.319 0.457 View mutations
66 L 9 10 19 0.526 0.514 View mutations
67 P 0 19 19 0.984 0.912 View mutations
68 F 6 13 19 0.674 0.660 View mutations
69 Q 19 0 19 0.000 0.263 View mutations
70 R 19 0 19 0.000 0.176 View mutations
71 L 0 19 19 0.940 0.820 View mutations
72 V 8 11 19 0.558 0.551 View mutations
73 R 1 18 19 0.924 0.631 View mutations
74 E 18 1 19 0.084 0.324 View mutations
75 I 19 0 19 0.028 0.383 View mutations