Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 R 4 15 19 0.812 0.511 View mutations
402 V 5 14 19 0.716 0.558 View mutations
403 D 0 19 19 0.997 0.688 View mutations
404 I 1 18 19 0.947 0.566 View mutations
405 W 12 7 19 0.429 0.461 View mutations
406 A 19 0 19 0.000 0.299 View mutations
407 F 19 0 19 0.028 0.379 View mutations
408 G 0 19 19 1.000 0.815 View mutations
409 L 18 1 19 0.053 0.251 View mutations
410 V 6 13 19 0.666 0.573 View mutations
411 L 1 18 19 0.927 0.587 View mutations
412 W 0 19 19 1.000 0.700 View mutations
413 E 0 19 19 1.000 0.754 View mutations
414 V 1 18 19 0.939 0.622 View mutations
415 A 6 13 19 0.692 0.524 View mutations
416 R 0 19 19 1.000 0.683 View mutations
417 R 0 19 19 0.990 0.705 View mutations
418 M 11 8 19 0.453 0.488 View mutations
419 V 6 13 19 0.644 0.504 View mutations
420 S 2 17 19 0.897 0.591 View mutations
421 N 17 2 19 0.113 0.406 View mutations
422 G 15 4 19 0.223 0.372 View mutations
423 I 5 14 19 0.740 0.556 View mutations
424 V 8 11 19 0.607 0.530 View mutations
425 E 19 0 19 0.016 0.261 View mutations